Frank Lampard has made three changes to the starting XI that beat Hull City 4-0 on Tuesday night.
The two sides face each other again this afternoon and the three midweek goalscorers Martyn Waghorn, Florian Jozefzoon and Mason Mount have retained their starting spots for the Sky Bet Championship clash.
Craig Bryson will make his 250th appearance for the club as he returns to the starting line up. David Nugent is also back in the starting XI as the pair replace Jack Marriott and Tom Huddlestone.
Scott Carson will be back in goal for the Rams, replacing Kelle Roos, as Derby look for their fourth consecutive clean sheet.
Tom Lawrence, who was not in the matchday squad for the Carabao Cup clash has been named as a substitute.
Hull City: Marshall, Lichaj, De Wijs, Burke, Evandro, Kane, Batty, Bowen, Hendriksen (C), Kingsley, Campbell
Substitutes: Long, Stewart, Dicko, Toral, Keane, McKenzie, Elphick
Derby County: Carson, Wisdom, Bryson, Tomori, Keogh (C), Mount, Waghorn, Jozefzoon, Johnson, Nugent, Malone
Substitutes: Forsyth, Lawrence, Bennett, Roos, Holmes, Bird, Huddlestone